Objective: To systematically evaluate cluster structure training (CS) and traditional training (TS) in enhancing athletes` motor abilities and explore sport-specific effects. Methods: Systematic searches of PubMed, Embase, Cochrane, and Web of Science (inception to March 2025). Quality was assessed using TESTEX, with meta-analyses calculating SMD (P < 0.05) and subgroup analyses by sport. Results: A total of 11 studies were included, showing that CS outperformed TS in improving athletes` sprint ability (SMD = -0.32, 95% CI: [-0.56, -0.07], P = 0.012), explosive power (SMD = 0.39, 95% CI: [0.10, 0.68], P = 0.009) with significant differences. Subgroup analysis further revealed sport-specific effects: CS was more effective than TS in enhancing maximum strength (SMD = 0.30, 95% CI: [0.01, 0.59], P = 0.043), explosive power (SMD = 0.96, 95% CI: [0.26, 1.65], P = 0.007), and sprint ability (SMD = -0.65, 95% CI: [-1.15, -0.16], P = 0.009) in volleyball athletes, as well as peak power in soccer athletes (SMD = 0.68, 95% CI: [0.01, 1.36], P = 0.047). Conclusion: CS benefits volleyball and soccer, where explosive power is key. Coaches should tailor CS to sports` energy demands and work-rest ratios.
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