Exercise and the kynurenine pathway: Current state of lnowledge and results from a randomized cross-over study comparing acute effects of endurance and resistance training
(Belastung/Bewegung und der Kynurenin-Pathway: Aktueller Wissensstand und Ergebnisse einer randomisierten Crossover-Studie, bei der akute Effekte von Ausdauer- und Krafttraining verglichen wurden)
Introduction: The essential amino acid tryptophan (TRP) is primarily degraded through the kynurenine (KYN) pathway, which is dysregulated in several chronic diseases. KYN pathway metabolites have immune- and neuro-modulatory properties and are involved in th de novo synthesis of nicotinamide adenine dinucleotide (NAD+). Currently, little evidence exists demonstrating that physical exercise may influence this pathway. However, differences between acute and chronic stimuli as well as the influence of exercise modalities remain to be investigated. Here, we provide an overview of existing studies and present results of a randomized cross-over trial on acute effects of a single-bout of resistance and endurance exercise.
© Copyright 2020 Exercise Immunology Review. Verein zur Förderung der Sportmedizin. Alle Rechte vorbehalten.
| Schlagworte: | |
|---|---|
| Notationen: | Trainingswissenschaft Biowissenschaften und Sportmedizin Ausdauersportarten Kraft-Schnellkraft-Sportarten |
| Veröffentlicht in: | Exercise Immunology Review |
| Sprache: | Englisch |
| Veröffentlicht: |
2020
|
| Online-Zugang: | http://eir-isei.de/2020/eir-2020-024-article.pdf |
| Jahrgang: | 26 |
| Heft: | 1 |
| Seiten: | 24-42 |
| Dokumentenarten: | Artikel |
| Level: | hoch |