Oxygen is transferred from air to mitochondria in sequential steps by means of diffusion and convection. The theoretical ceiling for whole body aerobic uptake may be determined by any factor influencing the O2 transport and utilization chain. The dispute considered here is whether peripheral O2 diffusion from microvessels, particularly capillaries, into active skeletal muscle fibres limits/regulates maximal oxygen uptake (VO2max) in healthy humans.
© Copyright 2015 The Journal of Physiology. Blackwell Publishing. Alle Rechte vorbehalten.