Background: Medial Tibial Stress Syndrome (MTSS) is identified as the most prevalent musculoskeletal injury among athletes, with an incidence rate between 13.6% and 20%, and a prevalence of 9.5%. Objective: The purpose of this study was to find the effects of tissue flossing with foam roller in medial tibial stress syndrome. Methods: This is a simple pre and post experimental design study. Two groups of 60 participants (30 athletes each) were allocated to the tissue flossing with foam roller group (group 1) and the ice massage with stretching exercise group (group 2). Difference in outcome scores were measured at the first day of treatment and five weeks later. Results: With an NPRS score of (3.8±1.2) compared to the group-2 (4.5±1.0), an LEFS score of 69.2±5.7 compared to the group-2 (66.4±5.6), and an MTSS score of (2.8±1.5) compared to the group-2 (3.9±1.4), the group-1 showed the mean difference improvement. Conclusion: Group 1 outperformed Group 2 in terms of the mean difference in NPRS, LEFS, and MTSS scores. The management of MTSS may involve tissue flossing along with foam rolling.
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