Genetic variants within NOGGIN, COL1A1, COL5A1, and IGF2 are associated with musculoskeletal injuries in elite male Australian Football League players: a preliminary study

(Genetische Varianten in NOGGIN, COL1A1, COL5A1 und IGF2 stehen in Zusammenhang mit Muskel-Skelett-Verletzungen bei männlichen Spielern der Australian Football League: eine vorläufige Studie)

Key Points - In this select cohort of elite Australian Football players, those with the rs1372857-NOGGIN GG or COL5A1 rs12722-TT genotype had a higher estimated number of total muscle-related injuries per game. However, those with the NOGGIN rs1372857-GG genotype also had a higher estimated number of moderate-to-high severity rated injuries. - The IGF2 rs3213221-CC genotype had a higher estimated number of contact tendon injuries per game, and a higher number of low severity rated injuries. - The rs1800012-TT genotype of COL1A1 had a higher number of ligament-related injuries per game, with significant associations seen between the genotype and low severity rated injuries. - The COL5A1 rs12722-TT genotype had a higher number of contact bone injuries per game, and a higher number of moderate severity rated injuries.
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Bibliographische Detailangaben
Schlagworte:
Notationen:Biowissenschaften und Sportmedizin Spielsportarten
Tagging:Australian Football Genotyp
Veröffentlicht in:Sports Medicine - Open
Sprache:Englisch
Veröffentlicht: 2022
Online-Zugang:https://doi.org/10.1186/s40798-022-00522-y
Jahrgang:8
Heft:126
Dokumentenarten:Artikel
Level:hoch