Genetic variants within NOGGIN, COL1A1, COL5A1, and IGF2 are associated with musculoskeletal injuries in elite male Australian Football League players: a preliminary study
Key Points
- In this select cohort of elite Australian Football players, those with the rs1372857-NOGGIN GG or COL5A1 rs12722-TT genotype had a higher estimated number of total muscle-related injuries per game. However, those with the NOGGIN rs1372857-GG genotype also had a higher estimated number of moderate-to-high severity rated injuries.
- The IGF2 rs3213221-CC genotype had a higher estimated number of contact tendon injuries per game, and a higher number of low severity rated injuries.
- The rs1800012-TT genotype of COL1A1 had a higher number of ligament-related injuries per game, with significant associations seen between the genotype and low severity rated injuries.
- The COL5A1 rs12722-TT genotype had a higher number of contact bone injuries per game, and a higher number of moderate severity rated injuries.
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| Subjects: | |
|---|---|
| Notations: | biological and medical sciences sport games |
| Tagging: | Australian Football Genotyp |
| Published in: | Sports Medicine - Open |
| Language: | English |
| Published: |
2022
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| Online Access: | https://doi.org/10.1186/s40798-022-00522-y |
| Volume: | 8 |
| Issue: | 126 |
| Document types: | article |
| Level: | advanced |