Introduction Hamstring muscle injuries (HMI) continue to plague professional football. Several scientific publications have encouraged a multifactorial approach; however, no multifactorial HMI risk reduction studies have been conducted in professional football. Furthermore, individualisation of HMI management programmes has only been researched in a rehabilitation setting. Therefore, this study aims to determine if a specific multifactorial and individualised programme can reduce HMI occurrence in professional football. Methods and analysis We conducted a prospective cohort study over two seasons within the Finnish Premier League and compare the amount of HMI sustained during a control season to an intervention season. Injury data and sport exposure were collected during the two seasons (2019-2020), and a multifactorial and individualised HMI risk reduction programme was be implemented during intervention season (2020). After a hamstring screening protocol is completed, individual training was be defined for each player within several categories: lumbo-pelvic control, range of motion, posterior chain strength, sprint mechanical output and an additional non-individualised `training for all players` category. Screening and respective updates to training programmes were conducted three times during the season. The outcome was to compare whether there was a significant effect of the intervention on the HMI occurrence using Cox regression analysis.
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