Repeated "all out" interval exercise causes an increase in serum hepcidin concentration in both trained and untrained men

This investigation assessed effects of high-intensity interval exercise (HIE; triple Wingate anaerobic test) on inflammatory markers, iron metabolism and hepcidin concentrations. Group of highly trained judo athletes (TR) and non-trained control males (CG) completed a triple Wingate test separated by 4.5 min rest. Venous blood samples were collected before, immediately after, 1 h, 24 h, and 5 days following exercise and analysed for serum of IL-6, IL-10, iron, and ferritin. Physiological response to exercise was also determined. Concentration of IL-6 and hepcidin increased 1 h after exercise in both groups (p < 0.05). Hepcidin returned post testing 24 h in TR, whereas in CG it remained elevated during 5 days following exercise. Changes in hepcidin did not correlate with shifts in serum IL-6, iron and ferritin concentrations. Gathered data suggest that following HIE, hepcidin increased independently of IL-6 and neither blood nor storage iron affected this phenomena. Originalartikel unter: https://www.researchgate.net/publication/249319391_Repeated_all_out_interval_exercise_causes_an_increase_in_serum_hepcidin_concentration_in_both_trained_and_untrained_men
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Bibliographic Details
Subjects:
Notations:biological and medical sciences combat sports
Published in:Cellular Immunology
Language:English
Published: 2013
Online Access:http://doi.org/10.1016/j.cellimm.2013.06.006
Volume:283
Pages:12-17
Document types:article
Level:advanced