4025145
What is the role of Titin in active muscle?
Several properties of muscle defy explanation solely based on the sliding filament-swinging cross-bridge theory. Indeed, muscle behaves as though there is a dynamic "spring" within the sarcomeres. We propose a new "winding filament" mechanism for how titin acts, in conjunction with the cross-bridges, as a force-dependent spring. The addition of titin into active sarcomeres resolves many puzzling muscle characteristics.
© Copyright 2012 Exercise and Sport Sciences Reviews. Lippincott Williams & Wilkins. Published by Lippincott Williams & Wilkins. All rights reserved.
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| Notations: | biological and medical sciences |
| Published in: | Exercise and Sport Sciences Reviews |
| Language: | English |
| Published: |
Hagerstown
Lippincott Williams & Wilkins
2012
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| Online Access: | http://doi.org/10.1097/JES.0b013e31824580c6 |
| Volume: | 40 |
| Issue: | 2 |
| Pages: | 73-78 |
| Document types: | article |
| Level: | advanced |