Beyond sports-doping headlines: The science of laboratory tests for performance-enhancing drugs
This primer on urine analysis in sports-doping control is an overview with an emphasis on the main analytical chemistry technologies in use: gas chromatography-mass spectrometry (GC-MS), liquid chromatography-tandem mass spectrometry (LC-MS-MS), isotope ratio mass spectrometry detection of exogenous testosterone use, and isoelectric focusing detection of recombinant erythropoietin (EPO) use. Included are graphic examples of GC-MS selected ion monitoring and full scan, LC-MS-MS, and EPO test electropherogram data; a list of common acronyms; and answers to questions frequently asked about tampering and test accuracy.
© Copyright 2007 Pediatric Clinics of North America. Elsevier. All rights reserved.
| Subjects: | |
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| Notations: | biological and medical sciences technical and natural sciences |
| Published in: | Pediatric Clinics of North America |
| Language: | English |
| Published: |
2007
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| Online Access: | https://doi.org/10.1016/j.pcl.2007.04.008 |
| Volume: | 54 |
| Issue: | 4 |
| Pages: | 713-733 |
| Document types: | article |
| Level: | advanced |