Effects of erythropoietin administration in training athletes and possible indirect detection in doping control

This study investigated the effects of repeated subcutaneous injection of rHuEpo (50 IU·kg-1) in athletes and proposes a method based on the measurement in blood samples of the sTfR/serum protein ratio to determine if the observed values of this marker are related to rHuEpo abuse. Result: When oxygen uptake measured at the VT was expressed as a percentage of VO2 max, the values obtained were also significantly higher. The increased values of Tfr and sTfr/serum proteins, respectively, above 10 µg·mL-1 and 153, indicated the probable intake of rHuEpo.
© Copyright 1999 Medicine & Science in Sports & Exercise. Lippincott Williams & Wilkins. All rights reserved.

Bibliographic Details
Subjects:
Notations:endurance sports biological and medical sciences
Published in:Medicine & Science in Sports & Exercise
Language:English
Published: 1999
Online Access:https://journals.lww.com/acsm-msse/Fulltext/1999/05000/Effects_of_erythropoietin_administration_in.3.aspx
Volume:31
Issue:5
Pages:639-645
Document types:article
Level:advanced