Resistance training induces many structural and functional benefits on the musculoskeletal system.1 Traditionally, resistance training has been prescribed according to recommendations of prominent health and professional organizations in the form of rigid, nonpersonalized training programs and constituent training variables. To illustrate, fixed structures of sets, repetitions, and rest intervals are prescribed alongside percentages of the maximal load a person can lift for a single repetition (1-repetition maximum [1RM]) in an exercise. Although this one-size-fits-all approach is promoted at group level, it fails to account for the variability of day-to-day performance. To explain, 1RM capabilities may be reduced on a random day due to fatigue, sleep deprivation, or inadequate dietary regimens. Moreover, the number of repetitions that can be completed against a given 1RM percentage is individual, exercise, and set specific. Therefore, prescribing resistance training based on rigid structures and 1RM percentages may lead to an overloading stimulus in some days and an underloading in others.
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