Suchergebnisse - Genes
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Collagen gene polymorphisms previously associated with resistance to soft-tissue injury are more common in competitive runners than nonathletes (Kollagen-Gen-Polymorphismen, die zuvor mit der Resistenz gegenüber Weichteilverletzungen in Verbindung gebracht wurden, sind bei Leistungssportlern häufiger als bei Nicht-Sportlern)
Dines, H. R., Nixon, J., Lockey, S. J., Herbert, A. J., Kipps, C., Pedlar, C. R., Day, S. H., Heffernan, S. M., Antrobus, M. R., Brazier, J., Erskine, R. M., Stebbings, G. K., Hall, E. C. R., Williams, A. G.Veröffentlicht in The Journal of Strength and Conditioning Research (2023)“… Single-nucleotide polymorphisms (SNPs) of collagen genes have been associated with soft-tissue injury and running performance. …”
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The relationship of blood lactate level and swimming performance with MCT1 after critical velocity (Die Beziehung zwischen Blutlaktatspiegel und Schwimmleistung mit MCT1 nach kritischer Geschwindigkeit)
Altan, B. K., Odabas, H. I., Hakan, M. T., Zeybek, S. U.Veröffentlicht in Annals of Applied Sport Science (2024)“… The investigation into whether the MCT1 gene in swimming and the inclusion of exercises involving critical velocity in water warm-ups have an effect on performance is ongoing. …”
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Training to enhance the physiological determinants of long-distance running performance. Can valid recommendations be given to runners and coaches based on current scientific knowl... (Training zur Verbesserung der physiologischen Determinanten der Langstreckenlaufleistung. Können Läufern und Trainern auf der Grundlage der aktuellen wissenschaftlichen Erkenntnisse gültige Empfehlungen gegeben werden?)
Midgley, A. W., McNaughton, L. R., Jones, A. M.Veröffentlicht in Sports Medicine (2007)“… In the future, molecular biology may make an increasing contribution in identifying effective training methods, by identifying the genes that contribute to the variation in maximal oxygen uptake, the lactate threshold and running economy, as well as the biochemical and mechanical signals that induce these genes. …”
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Effects of high-speed training on messenger RNA expression in two-year-old thoroughbred racehorses (Auswirkungen von Hochgeschwindigkeitstraining auf die Expression von Boten-RNA bei zweijährigen Vollblutrennpferden)
Johnson, M. G., Adam, E., Watt, A., Page, A. E.Veröffentlicht in Journal of Equine Veterinary Science (2023)“… Messenger RNA (mRNA) was isolated and used to analyze the expression of 34 genes via RT-qPCR. Statistical analysis of the noninjured horses (n = 6) showed that 13 genes were significantly correlated with increasing average weekly high-speed furlong performance. …”
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Whole-blood and peripheral mononuclear cell transcriptional response to prolonged altitude exposure in well-trained runners (Transkriptionsreaktion von Vollblut und peripheren mononukleären Zellen auf längere Höhenexposition bei gut trainierten Läufern)
Sutehall, S., Malinsky, F., Shurlock, J., Wang, G., Bosch, A., Pitsiladis, Y. P.Veröffentlicht in Clinical Journal of Sport Medicine (2023)“… There were no genes identified upon return to sea level in whole blood, and only one gene within PBMC. …”
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Genetic profile in genes associated with sports injuries in elite endurance athletes (Genetisches Profil von Genen, die mit Sportverletzungen bei Elite-Ausdauersportlern assoziiert sind)
Varillas-Delgado, D., Gutierrez-Hellín, J., Maestro, A.Veröffentlicht in International Journal of Sports Medicine (2023)“… Injuries are a complex trait that can stem from the interaction of several genes. The aim of this research was to examine the relationship between muscle performance-related genes and overuse injury risk in elite endurance athletes, and to examine the feasibility of determining a total genotype score that significantly correlates with injury. …”
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Bone mineral density in high-level endurance runners: part B—genotype-dependent characteristics (Knochenmineraldichte bei Hochleistungsausdauerläufern: Teil B - vom Genotyp abhängige Merkmale)
Herbert, A. J., Williams, A. G., Lockey, S. J., Erskine, R. M., Sale, C., Hennis, P. J., Day, S. H., Stebbings, G. K.Veröffentlicht in European Journal of Applied Physiology (2021)“… Method Ten single-nucleotide polymorphisms (SNPs) were identifed from previous genome-wide and/or candidate gene association studies that have a functional effect on bone physiology. …”
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HIF-1Alpha and NFIA_AS2 polymorphisms as potential determinants of total hemoglobin mass in endurance athletes (HIF-1Alpha- und NFIA-AS2-Polymorphismen als potenzielle Determinanten der Gesamthämoglobinmasse bei Ausdauersportlern)
Malczewska-Lenczowska, J., Orysiak, J., Majorczyk, E., Sitkowski, D., Starczewski, M., Zmijewski, P.Veröffentlicht in The Journal of Strength and Conditioning Research (2022)“… The aims of this study were to examine (1) the genotype distribution of rs11549465:C>T of the HIF-1a gene and rs1572312:C>A of the NFIA-AS2 gene; (2) the association between the genes and hematological status in endurance-oriented athletes; and (3) the association between the NFIA-AS2 gene and aerobic capacity in cyclists. …”
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Natación artística en niñas: antropometría, genotipo y rendimiento deportivo (Synchronschwimmen der Frauen: Anthropometrie, Genotyp und sportliche Leistung)
Romero-Lorca, A., de la Calle, L., Novillo, A., Fernández-Santander, A., Blanco, M.A., Rodelgo, T., Andreu-Vázquez, C., Gaibar, M.Veröffentlicht in Revista Internacional de Medicina y Sciencias de la Actividad y del deporte (2022)“… The data analysed were anthropometric measures, menarche age, genotype related to performance (gene ACTN3) and athletic performance. Relationships between athletic performance and anthropometric or genetic data were compared among the three age groups. …”
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GALNTL6 rs558129: A novel polymorphism for swimming performance? (GALNTL6 rs558129: Ein neuer Polymorphismus für die Schwimmleistung?)
Zmijewski, P., Trybek, G., Czarny, W., Leonska-Duniec, A.Veröffentlicht in Journal of Human Kinetics (2021)“… The enzyme polypeptide N-acetylgalactosaminyltransferase like 6, encoded by the GALANTL6 gene, plays a role in the gut microbiome regarding regulation of short-chain fatty acids and their anti-inflammatory and resynthesis functions. …”
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Rationale and design of the PROspective ATHletic Heart (Pro@Heart) study: long-term assessment of the determinants of cardiac remodelling and its clinical consequences in endurance... (Grundprinzip und Design der PROspective ATHletic Heart (Pro@Heart)-Studie: Langzeitbewertung der Determinanten des Herzumbaus und seiner klinischen Folgen bei Ausdauersportlern)
De Bosscher, R., Dausin, C., Janssens, K., Bogaert, J., Elliott, A., Ghekiere, O., Van De Heyning, C. M., Sanders, P., Kalman, J., Fatkin, D., Herbots, L., Willems, R., Heidbuchel, H., La Gerche, A., Claessen, G.Veröffentlicht in BMJ Open Sport & Exercise Medicine (2022)“… Genotype will be determined using a custom cardiomyopathy gene panel and high-density single-nucleotide polymorphism arrays. …”
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Genetics of bone mineral density and the associated influence on performance and stress fracture incidence in high-level endurance runners (Genetik der Knochenmineraldichte und des damit zusammenhängenden Einflusses auf die Leistung und von Stressfrakturen bei Hochleistungs-Langstreckenläufern)
Herbert, A. J.Veröffentlicht 2019“… Furthermore, few investigations have considered gene-environment interactions - in particular, whether specific genes may be sensitive to mechanical loading from physical activity and the outcome of such an interaction for BMD and potential stress fracture injury risk. …”
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Genetic basis for the dominance of Israeli long-distance runners of Ethiopian origin (Genetische Grundlage für die Dominanz der israelischen Langstreckenläufer äthiopischer Herkunft)
Ben-Zaken, S., Meckel, Y., Nemet, D., Kassem, E., Eliakim, A.Veröffentlicht in The Journal of Strength and Conditioning Research (2021)“… There was no difference in the frequency of AGT T/C gene polymorphism between the long-distance runners of Ethiopian and non-Ethiopian origin. …”
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The occurence of R577X polymorphism of ACTN3 gene in a selected group of elite fencers (Das Auftreten von R577X Polymorphismus des ACTN3-Gens in einer Gruppe von Fechtern des Spitzenbereichs)
Balkó, I., Balkó, S., Týnková, H., Kohlíková, E.Veröffentlicht in AUC Kinanthropologica (2014)“… The study concentrates on the comparison of speed-strenght abilities determined by Wingate test performed in the Biomedical laboratory of FTVS at Charles University in Prague and specific speed tests for fencing with R577X polymorphism of ACTN3 gene in elite fencers of the Czech Republic. By the analysis of buccal smear, we found that 80% of our sample of fencers contains in their genotype at least one R allele of the ACTN3 gene of the R577X polymorphism and 27% of the whole are homozygotes with RR genotype. …”
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Genetic characteristics of competitive swimmers: a review (Genetische Merkmale von Leistungsschwimmern: ein Überblick)
Ben-Zaken, S., Eliakim, A., Nemet, D., Kaufman, L., Meckel, Y.Veröffentlicht in Biology of Sport (2022)“… The current paper reviews the main findings on the leading 12 genetic polymorphisms (located in the ACE, ACTN3, AMPD1, BDKRB2, IGF1, IL6, MCT1, MSTN, NOS3, PPARA, PPARGC1A, and VEGFR2 genes) related to swimming performance, while taking into consideration the unique environment of this sport. …”
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Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism (Meta-omics-Analyse von Spitzensportlern identifiziert eine leistungssteigernde Mikrobe, die über den Laktatstoffwechsel funktioniert)
Scheiman, J., Luber, J. M., Chavkin, T., MacDonald, T., Tung, A., Pham, L.-D., Wibowo, M. C., Wurth, R. C., Punthambaker, S., Tierney, B. T., Yang, Z., Hattab, M. W., Avila-Pacheco, J., Clish, C. B., Lessard, S., Church, G. M., Kostic, A. D.Veröffentlicht in nature medicine (2019)“… Veillonella utilize lactate as their sole carbon source, which prompted us to perform a shotgun metagenomic analysis in a cohort of elite athletes, finding that every gene in a major pathway metabolizing lactate to propionate is at higher relative abundance postexercise. …”
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The interactions of physical activity, exercise and genetics and their associations with bone mineral density: implications for injury risk in elite athletes (Die Wechselwirkungen von körperlicher Aktivität, Training und Genetik und ihre Zusammenhänge mit der Knochenmineraldichte: Implikationen für das Verletzungsrisiko bei Leistungssportlern)
Herbert, A. J., Williams, A. G., Hennis, P. J., Erskine, R. M., Sale, C., Day, S. H., Stebbings, G. K.Veröffentlicht in European Journal of Applied Physiology (2019)“… Furthermore, few investigations have considered gene-environment interactions—in particular, whether specific genes may be sensitive to mechanical loading from physical activity and the outcome of such an interaction for BMD and potential injury risk. …”
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Form of Vitamin E supplementation affects oxidative and inflammatory response in exercising horses (Die Form der Vitamin-E-Supplementierung beeinflusst die oxidative und entzündliche Reaktion bei trainierenden Pferden)
Fagan, M. M., Harris, P., Adams, A., Pazdro, R., Krotky, A., Call, J., Duberstein, K. J.Veröffentlicht in Journal of Equine Veterinary Science (2020)“… Serum aspartate aminotransferase was lower after exercise in NAT horses versus SYN-L and SYN-H (P = .02), and less reduction in stride duration was seen after exercise in NAT as compared with SYN-L and SYN-H (P = .02). Gene expression of tumor necrosis factor a was lower in NAT compared with SYN-H (P = .01) but not SYN-L. …”
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ACTN3 genotype influences exercise-induced muscle damage during a marathon competition (ACTN3-Genotyp beeinflusst trainingsinduzierte Muskelschäden während eines Marathonwettbewerbs)
Del Coso, J., Valero, M., Salinero, J. J., Lara, B., Díaz, G., Gallo-Salazar, C., Ruiz-Vicente, D., Areces, F., Puente, C., Carril, J. C., Cacabelos, R.Veröffentlicht in European Journal of Applied Physiology (2017)“… Conclusions: In comparison to RR homozygotes, X allele carriers for the R577X polymorphism of the ACTN3 gene presented higher values for typical markers of exercise-induced muscle damage during a competitive marathon. …”
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Association of genetic variances in ADRB1 and PPARGC1a with two-kilometre running time-trial performance in Australian Football League players: A preliminary study (Beziehung zwischen genetischen Varianzen bei ADRB1 und PPARGC1 mit der Testleistung im 2-km-Lauf von Spielern der Australian Football League: ein vorläufiger Bericht)
Jacob, Y., Anderton, R. S., Cochrane Wilkie, J. L., Rogalski, B., Laws, S. M., Jones, A., Spiteri, T., Hart, N. H.Veröffentlicht in Sports (2021)“… This study assessed the influence of polymorphisms in these candidate genes towards endurance test performance in 46 players from a single Australian Football League (AFL) team. …”