This study compared weekly training-load (TL), training-monotony (TM), and training-strain (TS) in 80 professional football players (28.1 ± 3.2 yrs, 78.0 ± 5.9 kg, and 182.0 ± 4.8 cm), considering two lengths (6 and 7 days between matches), two types of periodization strategies (placing the compensatory session in MD+1 [P1] or MD+2 [P2] post-match-day) and two players` status, starters, and non-starters. Using Global Positioning Technology, the monitored variables were: Player Load (PL), Total Distance (TD), distances at various speeds (>21 [HSR], >24 [VHSR], and > 27 [SPR] km·h-1), number of accelerations (>2 m·s-2, ACC), and decelerations (<-2 m·s-2, DEC). Kruskal-Wallis and Mann-Whitney non-parametric statistical tests were used for loading strategy differences. In both lengths and periodization strategies of the micro-cycles, non-starters trained more than starters. There were differences in the quantity (TL) and distribution (TM and TS) demand considering the micro-cycle`s length and periodization strategy. In MD+1 (P1), non-starters accumulated higher TL, showing moderate to large Cohen`s d magnitudes in HSR, VHSR, SPR, PL, and TD. For starters, training in MD+2 (P2) resulted in higher values (p < 0.05) of TL, TM and TS. The coaching staff needs to anticipate TL, TM, and TS by considering players` status, periodization strategy, and the number of training sessions between matches.
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